Xbox 360 game discs can be a mess, and it’s not just because they’re filled with games. They can also be a breeding ground for bacteria, and that’s why it’s important to clean them regularly. To clean a Xbox 360 game disc, you’ll need toothpaste. Apply the toothpaste to the inside of the discolored area, and then use a cloth or paper towel to help remove any excess toothpaste. Be sure to keep the area dry so that the cleaning process doesn’t cause any damage to the disc.